top of page
xJohn Huffman_edited_edited.jpg


John W. Huffman,
Ph. D

In Memorium

John W. Huffman, PH. D.

John W. Huffman, Ph.D., was a scientific advisor to Immugen for the past 9 years but his contributions will be remembered more for the compounds that he made available to the research community as a whole. Perhaps no other organic chemist’s output has contributed more to the understanding of the peripheral endocannabinoid system than his highly selective ligands, JWH-015 and JWH-133, perhaps the two most widely used by the scientific community. These compounds have allowed scientists to explore the role of the endocannabinoid system as it relates to pain, inflammation, neurodegenerative diseases, cancer, cardiovascular, gastrointestinal, musculoskeletal, reproductive systems and infectious diseases, including HIV. Other highly selective compounds exist but their effects have not been studied as much as his classical cannabinoid derivatives and aminoalkylindoles that have resulted in the publication of more than 400 peer-reviewed articles.

bottom of page